The BIOFIRE System and Your Immune System

The BIOFIRE System offers syndromic testing for infectious diseases, allowing healthcare professionals to select the right test first time. Patients benefit from faster diagnoses and more targeted therapy. Clinicians benefit from improved stewardship for antibiotics. Labs are more efficient and can make cost savings.

The BioFire FilmArray Pneumonia plus panel (PN panel) analyzes native sputum endotracheal aspirate, and bronchoalveolar specimens (including mini-BAL) for 33 pathogens with clinical relevance and antimicrobial resistance genes, with semiquantitative results in about an hour.

Respiratory

The burning of biomass, such as wood, plants and other organic materials, produces gaseous pollutants and fine particulates that negatively affect the respiratory system. Climate change could make it more difficult to reverse the negative effects of forest fires to human health.

In the United States wildfire smoke is associated with hospitalizations caused by respiratory diseases such as asthma, COPD, and lung cancer. Furthermore, this type of air pollution is an important risk factor for cardiovascular disease and a major cause of illness for the most vulnerable population that include those with lower socioeconomic status (SES).

During the COVID-19 pandemic, a number of communities were exposed levels of air pollution due to wildfires. The response of public health has been limited to a communication campaign about symptom management. This knowledge gap is alarming considering the evidence that smoking and other sources of air pollution can lead to health issues.

Researchers are now looking at the best methods to safeguard public health in future events of this kind. NIH is a research institution that studies this crucial public health issue through the BLUE CORAL and FIRE CORAL studies.

For the first time an prospective study will assess the long-term effects of exposure to smoke from wildfires and other sources. FIRE CORAL recruits adult participants who are hospitalized for COVID-19 index episode and speak English or Spanish but aren't pregnant. The FIRE CORAL protocol includes a series of tests conducted in-person, objectively measuring the pulmonary function test and lung imaging and functional assessment.

The lungs are the most sensitive to the effects of smoke and other particles since they can trigger or worsen chronic respiratory conditions like emphysema or COPD, and increase the risk of developing pneumonia. There are a variety of steps that can be taken to stop or lessen the negative health effects of exposure to smoke, which includes abstaining from outdoor activities when it is feasible and wearing the EPA's "N95" mask that is designed to catch fine particles.

Smoking cigarettes can cause irritation to the throat and eyes and cause a runny nose. To help reduce symptoms, drink plenty of water, and take medications that reduce inflammation, like corticosteroids.

Bloodstream

Your bloodstream is on the front lines of fighting off germs that enter your body. Dendritic cells, which are special cells, are like the fire department's call center. they collect the antigens (molecules that trigger an immune response) from germs that are invading your body and then release proteins that signal other white blood cells to to fight them. The total white blood cells, differentials and band cells increased following firefighters' fire-fighting duties, compared to levels after strenuous exercise without fire-fighting.

Skin

Dermatologists were concerned about the smoke and ash that resulted from the California wildfires could cause negative effects on the skin of those exposed to the smoke and ash. Maria Wei is a graduate student at the University of California, Irvine. She studies how extreme wildfire pollution impacts the skin. Her research was published on April 22, 2012 in Scientific Reports.

Wei's research has shown that the temperature of the skin varies based on how long the body is exposed to flames. It could take up to two hours for the skin of someone to reach their "flash point"--the place where it begins to burn and then turns into ash. This is the reason why it's essential to stay away from the campfire or a fire, and why you must wear protective clothing when you go outside during a forest fire or even the heat of the day.

Forest fires will continue occur, despite the measures taken to stop fires from causing pollution. Wei is predicting that the number of people suffering the effects of wildfires will grow as climate change causes more and more forests to be burned. This means that more people will need to wear long sleeves and hats and also thick moisturizers.

Wildfire air pollution can also cause atopic dermatitis to the skin, which causes itchy skin in a lot of people. She suggests that this is due to the particles in smoke can block pores, which makes the condition worse.

Atopic dermatitis may make people more sensitive towards UV light. This can be exacerbated by smoke from wildfires. This can result in people seeking out tanning salons and apply a tan with less protection.

A fire and ice treatment can help reduce atopic skin symptoms of dermatitis however it is not recommended for those with an open wound or rash. Patients with active acne should be cautious If you're pregnant or breastfeeding it's recommended to stay clear of this treatment completely. The IS Clinical Fire & Ice Facial at Novuskin, Las Vegas' premiere membership MedSpa, is an intensive and effective facial that bridges the gap between a gentle facial and a peel without needing any downtime. It's designed to rejuvenate the skin, improve the appearance of rosacea, lessen acne scarring, reduce wrinkles, and promote cellular renewal. This is a great way to give your skin a glowing glow.

Infections

The human body is a complex system of organs and tissues that work to guard us against infections. Infections can be caused by microorganisms, such as parasites, viruses, and bacteria that infect healthy cells and cause them to multiply uncontrollably. If this happens, your immune system may react by displaying symptoms of illness. These symptoms could be anything from a snoring nose to an upset stomach as well as a fever, swollen lymph glands or an itchy skin rash. Your symptoms can be affected by the type of infection, its location, and even your temperature.

Infections can spread through different ways, Bio ethanol fireplaces but they are most often spread through droplets in the air that remain after a sniff or cough. Bacterial infections like tuberculosis, strep throat, meningococcal diseases and Legionnaires' disease are spread through this method, along with certain viral infections such as the common cold and influenza. Certain bacterial infections like skin infections or sexually transmitted diseases (STIs) such as gonorrhea or chlamydia are spread by direct contact with infected mucous surfaces or tissues, or indirectly by contaminated surfaces. Certain bacterial infections are transmitted by insects, such as ticks, fleas, or indoor bioethanol Fireplace mosquitoes.

Some parasites and viruses are small enough to enter your bloodstream and infect your cells, which can cause serious illness like the common cold or AIDS. Fungi can cause skin conditions such as ringworm and athlete's foot and some can affect the lungs and nervous system.

The BioFire Panel uses our innovative FilmArray technology to analyze the bronchoalveolar and sputum samples to determine a comprehensive list of pathogens involved in upper respiratory infections. The kit includes an reagent pouch that houses all the necessary chemicals to perform reverse transcription PCR, nested multiplex analysis and detection on a single machine. It's an easy-to-use solution to aid clinicians in identifying and treat patients with various respiratory symptoms. This test has been granted an Emergency Use Authorization and is available through bioMerieux's CLIA moderate and Bio fireplaces high-complexity labs.